In recent years, a growing amount of evidence has linked the antioxidant resveratrol to numerous brain health benefits. However, most studies have been observational, linking dietary consumption to improved cognition, or were conducted in animals. This has prevented scientists from being able to make any hard claims about the nutrient's effects on the brain.
This may soon change, as a team of researchers from Georgetown University is currently enrolling participants into a clinical study looking at the effects of resveratrol on brain health. The investigation could deliver the first definitive evidence of the nutrient's actions in the mind.
"Most resveratrol studies showing any health benefits have been conducted in animal models, such as mice, and with doses that far exceed intake from sipping wine or nibbling on chocolate," said lead researcher Scott Turner. "With this clinical trial, we'll find out if daily doses of pure resveratrol can delay or alter memory deterioration and daily functioning."
In the study, team will administer either daily supplements containing the nutrient or a placebo to a group participants. Each individual will have his or her cognitive function tested several times throughout the one-year study period. The researchers will then compare results from each group.
The team described this sort of randomized control trial as the "gold standard" of scientific investigations. It will provide the hardest evidence to date of the effects of resveratrol on cognition.
Findings from the study could be used to help doctors develop recommendations for patients by showing them exactly what doses of the nutrient are appropriate. This may make resveratrol supplementation much more common among people who are looking to support their brain health.
